CALL FOR PAPERS Integrative and Translational Physiology: Integrative Aspects of Energy Homeostasis and Metabolic Diseases High-protein diet selectively reduces fat mass and improves glucose tolerance in Western-type diet-induced obese rats
نویسندگان
چکیده
Andreas Stengel, Miriam Goebel-Stengel, Lixin Wang, Eugenia Hu, Hiroshi Karasawa, Joseph R. Pisegna, and Yvette Taché CURE/Digestive Diseases Research Center, Center for Neurobiology of Stress, Department of Medicine, Digestive Diseases Division at the University of California Los Angeles, and VA Greater Los Angeles Health Care System, Los Angeles, California; Charité Center for Internal Medicine and Dermatology, Division Psychosomatic Medicine, Obesity Center Berlin; Charité Universitätsmedizin Berlin, Berlin, Germany; and Department of Internal Medicine, Institute of Neurogastroenterology and Motility; Martin-Luther Hospital, Berlin, Germany
منابع مشابه
Low-carbohydrate diets affect energy balance and fuel homeostasis differentially in lean and obese rats.
In parallel with increased prevalence of overweight people in affluent societies are individuals trying to lose weight, often using low-carbohydrate diets. Nevertheless, long-term metabolic consequences of those diets, usually high in (saturated) fat, remain unclear. Therefore, we investigated long-term effects of high-fat diets with different carbohydrate/protein ratios on energy balance and f...
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Williams DB, Wan Z, Frier BC, Bell RC, Field CJ, Wright DC. Dietary supplementation with vitamin E and C attenuates dexamethasone-induced glucose intolerance in rats. Am J Physiol Regul Integr Comp Physiol 302: R49–R58, 2012. First published October 26, 2011; doi:10.1152/ajpregu.00304.2011.—Glucocorticoid excess induces marked insulin resistance and glucose intolerance. A recent study has shown...
متن کاملKnockdown of neuropeptide Y in the dorsomedial hypothalamus reverses high-fat diet-induced obesity and impaired glucose tolerance in rats.
Neuropeptide Y (NPY) in the dorsomedial hypothalamus (DMH) plays an important role in the regulation of energy balance. While DMH NPY overexpression causes hyperphagia and obesity in rats, knockdown of NPY in the DMH via adeno-associated virus (AAV)-mediated RNAi (AAVshNPY) ameliorates these alterations. Whether this knockdown has a therapeutic effect on obesity and glycemic disorder has yet to...
متن کاملChanges in glucose tolerance and leptin responsiveness of rats offered a choice of lard, sucrose, and chow.
Rats offered chow, lard, and 30% sucrose solution (choice) rapidly become obese. We tested metabolic disturbances in rats offered choice, chow+lard, or chow+30% sucrose solution [chow+liquid sucrose (LS)] and compared them with rats fed a composite 60% kcal fat, 7% sucrose diet [high-fat diet (HFD)], or a 10% kcal fat, 35% sucrose diet [low-fat diet (LFD)]. Choice rats had the highest energy in...
متن کاملIsolated duodenal exclusion increases energy expenditure and improves glucose homeostasis in diet-induced obese rats.
Roux-en-Y gastric bypass (RYGB) in rodent models reduces food intake (FI), increases resting energy expenditure (EE), and improves glycemic control. We have shown that mimicking the duodenal component of RYGB by implantation of a 10-cm endoluminal sleeve device (ELS-10) induces weight loss and improves glycemic control in diet-induced obese (DIO) rats. We sought to determine the mechanisms and ...
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تاریخ انتشار 2013